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Skin is an organ, and by weight it outweighs the liver and the brain in a typical adult.

Biology Facts, sourced to MedlinePlus.

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It runs to a few kilograms in an adult and covers close to two square meters. It is not simply a wrapper either. Skin regulates temperature, blocks pathogens, senses pressure and heat, resists water loss and manufactures vitamin D when sunlight falls on it. The outer layer is entirely replaced every few weeks, which is where a good deal of household dust comes from.

The claim comes from MedlinePlus.

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